Download PDF by Martha C. Johnson (auth.), Dr. Ismail Jatoi, Prof. Dr.: Management of Breast Diseases

By Martha C. Johnson (auth.), Dr. Ismail Jatoi, Prof. Dr. Manfred Kaufmann (eds.)

This multi-authored and finished paintings presents a connection with the final administration of illnesses of the breast (both benign and malignant). Pertinent controversies are mentioned, and views awarded from either side of the Atlantic. This hugely functional advisor serves as a reference for the wide variety of physicians and surgeons who deal with ailments of the breast.

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146 (3):706–16 49. Gudjonsson T et al (2002) Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition. J Cell Sci. 115(Pt 1):39–50 50. Schmeichel KL, Weaver VM, Bissell MJ (1998) Structural cues from the tissue microenvironment are essential determinants of the human mammary epithelial cell phenotype. J Mammary Gland Biol Neoplasia. 3(2):201–13 51. Radice GL et al (1997) Precocious mammary gland development in P-cadherin-deficient mice.

In humans, transplacental transport of immunoglobulins provides humoral immunity to the newborn for the first weeks of life. This protection is complemented by IgA and lactoferrin, a protein with antimicrobial properties, in the colostrum. These proteins are able to cross the epithelium lining the infant digestive tract intact [240]. Beginning about 36 h after parturition, milk volume increases more than tenfold [241]. Tight junctions in the breast are tightly closed during lactation [93] and this decrease in permeability is accompanied by an increase in milk secretion.

J Cell Biol. 110(4):1405–15 81. Pullan S et al (1996) Requirement of basement membrane for the suppression of programmed cell death in mammary epithelium. J Cell Sci. 109(Pt 3):631–42 82. Streuli C (1999) Extracellular matrix remodelling and cellular differentiation. Curr Opin Cell Biol. 11(5):634–40 83. Novaro V, Roskelley CD, Bissell MJ (2003) Collagen-IV and laminin-1 regulate estrogen receptor alpha expression and function in mouse mammary epithelial cells. J Cell Sci. 116(Pt 14):2975–86 84.

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