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More subtle deficiencies in implantation are likely to be part of the processes leading to obstetric diseases, such as pre-eclampsia or intrauterine growth restriction later in pregnancy. Inappropriate implantation may also, although more rarely, lead to morbid adherence of the placenta in conditions such as placenta accreta. Embryology – week by week This is the period from the appearance of the primitive streak, day 15 of development, until the end of the eighth week, that is, approximately 10 weeks from the first day of the last menstrual period.

By this means, the desaturated blood from the right ventricle passes down the aorta to enter the umbilical arterial circulation and thence to the placenta. Prior to birth, the ductus remains patent owing to the production of prostaglandin E2 and prostacyclin, which act as local vasodilators. Premature closure of the ductus has been reported with the administration of cyclo-oxygenase inhibitors. At birth, the cessation of umbilical blood flow causes cessation of flow in the ductus venosus, a fall in pressure in the right atrium and closure of the foramen ovale.

G. double or small heads or tails). The pH of the seminal fluid favours the sperm and Clinical importance Sperm production may be affected by medication and drugs, alcohol and lifestyle activities as well as by infection and disease processes. Obstruction to sperm movement from the testis through the epididymis and vas deferens may result from several causes. Congenital conditions, infections, diseases, blockage following surgery may all prevent the release of sperm. In addition, certain drugs and the impact of psychological conditions may influence effective sexual functions.

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