By Glenn L. Schattman, Sandro C. Esteves, Ashok Agarwal
Written and edited through best, across the world well-known clinicians and scientists in reproductive drugs and comparable fields, this exact textual content is a realistic and accomplished assessment of the scientific and medical value of unexplained female and male infertility and its administration. The ebook is split into thematic sections to make sure the main helpful presentation of issues, beginning with definitions and epidemiology of unexplained infertility, together with dialogue of the WHO’s cutoff values for human semen features and its ramifications. Sections masking female and male reproductive pathophysiology stick to respectively, overlaying organic, genetic and environmental causative elements, with a next part on evaluative ideas for female and male sufferers. Expectant, clinical and surgical procedure techniques contain the 5th component to the ebook, the place lively interventions and results of every remedy modality are rigorously thought of. the ultimate part discusses assisted reproductive strategies to regulate unexplained infertility, similar to intrauterine insemination and in vitro fertilization, in addition to destiny views. considerate and enlightening, Unexplained Infertility: Pathophysiology, assessment and remedy will be a useful source for all clinicians and scientists operating within the fields of reproductive drugs and infertility.
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Additional resources for Unexplained Infertility: Pathophysiology, Evaluation and Treatment
Smith S, Pfiefer, SM, Collins J, Diagnosis and management of female infertility. JAMA. 2003;290(13):1767–70. 30. Aboulghar MA, Mansour RT, Serour GI, Al-Inany HG. Diagnosis and management of unexplained infertility: an update. Arch Gynecol Obstet. 2003 Feb;267(4):177–88. 31. Isaksson R, Tiitinen A. Present concept of unexplained infertility. Gynecol Endocrinol. 2004 May;18(5):278–90. 32. Polyzos NP, Tzioras S, Mauri D, Tsappi M, Cortinovis I, Tsali L, Casazza G. Treatment of unexplained infertility with aromatase inhibitors or clomiphene citrate: a systematic review and metaanalysis.
Male factor infertility should have been ruled out with at least two normal semen analyses and with no demonstrable physical or endocrine abnormalities . The latest opinion paper by the Practice Committee of the American Society for Reproductive Medicine (ASRM) published in 2012  on the diagnostic evaluation of the infertile female, which replaces the 2006 document titled “Optimal evaluation of the infertile female” is a step forward towards understanding female infertility. Evaluation according to this document should include: 1.
Semen quality must be interpreted within the context of the patient’s clinical information. The male infertility evaluation must go far beyond a simple semen analysis, as it has to be complemented with a proper physical examination, a comprehensive history taking, and relevant endocrine, genetic, and other investigations. 18 Fig. 1 Modified semen analysis report template. The main difference from the routinely used templates is the inclusion of the “centile” distribution of semen characteristics from the reference population rather than S.